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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATM All Species: 9.09
Human Site: T1227 Identified Species: 22.22
UniProt: Q13315 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13315 NP_000042.3 3056 350687 T1227 E W L N L Q D T E Y N L S S F
Chimpanzee Pan troglodytes XP_001139487 3056 350692 T1227 E W L N L Q D T E Y N L S S F
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q62388 3066 349469 T1230 E W L N L Q D T E Y S L S S F
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001155872 3050 347768 G1224 W L K I K D S G Y S L S A F P
Frog Xenopus laevis Q9DE14 2654 301441 F951 Y K K P I C Q F L I E S L H S
Zebra Danio Brachydanio rerio XP_002667249 1913 215524 A210 S L L K K L P A E V A S L D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q5EAK6 2767 317973 R1064 Q S M S S C H R Q T V R D L I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001107666 3120 349933 Q1267 F L V Y Q W L Q E S Y E I R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M3G7 3856 435096 H2011 A E P K Y F I H F C S H W L L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RZT9 2939 328678 A1194 Q I L Y T W L A I D S I D E I
Conservation
Percent
Protein Identity: 100 99.4 N.A. N.A. N.A. 83.8 N.A. N.A. N.A. 69.5 20.5 35.1 N.A. 22.1 N.A. N.A. 36.2
Protein Similarity: 100 99.7 N.A. N.A. N.A. 91.3 N.A. N.A. N.A. 82.8 39.9 46.3 N.A. 42.8 N.A. N.A. 56.7
P-Site Identity: 100 100 N.A. N.A. N.A. 93.3 N.A. N.A. N.A. 0 0 13.3 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. N.A. N.A. 100 N.A. N.A. N.A. 6.6 6.6 13.3 N.A. 26.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 23.9 N.A. 20.8
Protein Similarity: N.A. N.A. N.A. 42.5 N.A. 40.9
P-Site Identity: N.A. N.A. N.A. 0 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 20 0 0 10 0 10 0 0 % A
% Cys: 0 0 0 0 0 20 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 30 0 0 10 0 0 20 10 0 % D
% Glu: 30 10 0 0 0 0 0 0 50 0 10 10 0 10 10 % E
% Phe: 10 0 0 0 0 10 0 10 10 0 0 0 0 10 30 % F
% Gly: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 10 0 0 0 10 0 10 0 % H
% Ile: 0 10 0 10 10 0 10 0 10 10 0 10 10 0 20 % I
% Lys: 0 10 20 20 20 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 30 50 0 30 10 20 0 10 0 10 30 20 20 10 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 30 0 0 0 0 0 0 20 0 0 0 0 % N
% Pro: 0 0 10 10 0 0 10 0 0 0 0 0 0 0 20 % P
% Gln: 20 0 0 0 10 30 10 10 10 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 10 0 10 0 % R
% Ser: 10 10 0 10 10 0 10 0 0 20 30 30 30 30 10 % S
% Thr: 0 0 0 0 10 0 0 30 0 10 0 0 0 0 0 % T
% Val: 0 0 10 0 0 0 0 0 0 10 10 0 0 0 0 % V
% Trp: 10 30 0 0 0 20 0 0 0 0 0 0 10 0 0 % W
% Tyr: 10 0 0 20 10 0 0 0 10 30 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _